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Index > Protein center > Gpx4(Gene name) > Mouse
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  • Gpx4 (Gene name),
  • Phospholipid hydroperoxide glutathione peroxidase, nuclear (Protein name ),  GPX42_MOUSE from NCBI database.
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  • Gene name:
    Gpx4;
    Protein name:
    Phospholipid hydroperoxide glutathione peroxidase, nuclear;
    Alternative:
    Glutathione peroxidase 4(GPx-4;GSHPx-4);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Stabilizes the condensed chromatin in sperm nuclei and is necessary for male fertility.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    253
    Sequence:
    50:
    MGRAAARKRG | RCRQRGGSPR | GRRRRGPGRQ | SPRKRPGPRR | RKARARRRRR | 
    100:
    ARPRRMEPIP | EPFNPGPLLQ | EPPQYCNSSE | FLGLCASRDD | WRCARSMHEF | 
    150:
    SAKDIDGHMV | CLDKYRGFVC | IVTNVASQUG | KTDVNYTQLV | DLHARYAECG | 
    200:
    LRILAFPCNQ | FGRQEPGSNQ | EIKEFAAGYN | VKFDMYSKIC | VNGDDAHPLW | 
    250:
    KWMKVQPKGR | GMLGNAIKWN | FTKFLIDKNG | CEVKRYGPME | EPQVIERDLP | 
    253:
    CYL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
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    E9951m
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    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
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    E9951h
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    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    E9951b
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    Packing:
    96T
    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    E9951m
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    Packing:
    96T
    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    E9951r
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    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    E9951p
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    Packing:
    96T
    ELISA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
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    E9951r
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    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    U9951p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    P9951Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    P9951Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    P9951Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    P9951Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Cat.:
    P9951Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Polyclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Monoclonal Antibody for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear
    Protein for Mouse Phospholipid hydroperoxide glutathione peroxidase, nuclear

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    References
    1. 1.
      "Identification of a specific sperm nuclei selenoenzyme necessary for protamine thiol cross-linking during sperm maturation."
      Pfeifer H. , Conrad M. , Roethlein D. , Kyriakopoulos A. , Brielmeier M. , Bornkamm G.W. , Behne D.
      FASEB J.15:1236-1238(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Testis.
    2. 2.
      "Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene."
      Imai H. , Hirao F. , Sakamoto T. , Sekine K. , Mizukura Y. , Saito M. , Kitamoto T. , Hayasaka M. , Hanaoka K. , Nakagawa Y.
      Biochem. Biophys. Res. Commun.305:278-286(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/SvJ.
      tissue: Liver.
    3. 3.
      "The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults."
      Yant L.J. , Ran Q. , Rao L. , Van Remmen H. , Shibatani T. , Belter J.G. , Motta L. , Richardson A. , Prolla T.A.
      Free Radic. Biol. Med.34:496-502(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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